I'm slowly working my way through a new playthrough on this patch and everything is running great so far. I can confirm that killing the Old Citizen in GMS no longer breaks the game (yay, genocide!), and it seems to me like a lot of old areas have been touched up a bit visually since the last patch. Maybe it's just me.
I love that SGS soldiers now show up when you clear out the outposts, and I'm kinda surprised by just how many there are! One of them actually patrols around!
I haven't been upping my Intimidation stat because I'm testing out Mercantile, but I wonder what would've happened if I left M'lan Ratula alive in the last outpost? A peaceful coexistence, perhaps?
Working my way through Junkyard now, and I am really excited to see the changes to the Elwood quest (finally!!).
On another note, I haven't noticed any significant changes to dialogue so far besides improvements to the Feat descriptions, but I did kinda gloss through Old Jonas' text so I may have missed it (unless the option for him to give you directions to Junkyard is new; I did notice that).
All in all, it's working great so far. Thanks, StygSoft! <3
EDIT: One thing I forgot to mention (but found incredibly humorous) is the fact that you can now tell Gorsky about how you helped out the people being held hostage by raiders in GMS even if you totally massacred both the raiders and their hostages, and his response will be the same as if you had just killed the raiders.
Yes, Gorsky, I certainly "helped" those poor souls. xD